PDZD3 / Unconjugated /
PDZD3 / Unconjugated /
Product Details
| Supplier | Aviva Systems Biology | |
|---|---|---|
| Catalog #: | OAAB13070 (View supplier product page) | |
| Size | 400 μl | |
| Price | $320.00 | |
| Antigen | PDZD3 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | Ig | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | WB | |
| Description | PDZD3 antibody - center region |
About PDZD3 and Purified
| PDZD3 | Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).[supplied by OMIM, Mar 2008] |
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Citations
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