PDHA1 / Unconjugated /
PDHA1 / Unconjugated /
Product Details
Supplier | Aviva Systems Biology | |
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Catalog #: | OAAB06248 (View supplier product page) | |
Size | 400 μl | |
Price | $320.00 | |
Antigen | PDHA1 | |
Clone | ||
Host | Rabbit | |
Isotype | Ig | |
Conjugate | Unconjugated | |
Target Species | Human | |
Applications | WB, ELISA | |
Description | PDHA1 Antibody - middle region (OAAB06248) Unconjugated Rabbit Polyclonal Antibody, Reacts with Human |
About PDHA1 and Purified
PDHA1 | The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010] |
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