PCDHGA10 / Unconjugated / 3A7
PCDHGA10 / Unconjugated / 3A7
Product Details
| Supplier | Aviva Systems Biology | |
|---|---|---|
| Catalog #: | OAAL00745 (View supplier product page) | |
| Size | 100 μg | |
| Price | $315.00 | |
| Antigen | PCDHGA10 | |
| Clone | 3A7 | |
| Host | Mouse | |
| Isotype | IgG2a κ | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | ELISA | |
| Description | PCDHGA10 Antibody (OAAL00745) Unconjugated Mouse Monoclonal Antibody, Reacts with Human |
About PCDHGA10 and Purified
| PCDHGA10 | This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008] |
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Citations
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