NOD2 / Unconjugated / 26mNOD2
NOD2 / Unconjugated / 26mNOD2
Product Details
Supplier | Aviva Systems Biology | |
---|---|---|
Catalog #: | OALA05298 (View supplier product page) | |
Size | 50 μg | |
Price | $395.00 | |
Antigen | NOD2 | |
Clone | 26mNOD2 | |
Host | Rat | |
Isotype | IgG1 κ | |
Conjugate | Unconjugated | |
Target Species | Mouse | |
Applications | IHC-P, WB | |
Description | NOD2 Antibody (OALA05298) Unconjugated Rat Monoclonal Antibody, Reacts with Mouse |
About NOD2 and Purified
NOD2 | This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2014] |
---|