NECAB3 / Unconjugated /
NECAB3 / Unconjugated /
Product Details
| Supplier | Aviva Systems Biology | |
|---|---|---|
| Catalog #: | OASG00439 (View supplier product page) | |
| Size | 100 μl | |
| Price | $215.00 | |
| Antigen | NECAB3 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Mouse | |
| Applications | WB, IHC, IF, ELISA | |
| Description | NECAB3 Antibody - C-terminal region (OASG00439) Unconjugated Rabbit Polyclonal Antibody, Reacts with Human, Mouse |
About NECAB3 and Purified
| NECAB3 | The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Citations
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