INCA1 / Unconjugated /
INCA1 / Unconjugated /
Product Details
| Supplier | Aviva Systems Biology | |
|---|---|---|
| Catalog #: | OAPB01013 (View supplier product page) | |
| Size | 100 μg | |
| Price | $375.00 | |
| Antigen | INCA1 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Mouse, Rat | |
| Applications | ELISA, WB | |
| Description | INCA1 was isolated through a yeast triple hybrid approach to identify interaction partners of the cyclin A1-CDK2 heterodimer. INCA1 is evolutionarily conserved and has no homology to any known proteins. Like Cyclin A1, INCA1 is highly expressed in testis with highest levels observed at various points of testis maturation. It has been suggested that the complex of INCA1 and the cyclinA1-CDK2 dimer plays a role in several signaling pathways important for cell cycle control and meiosis. Recent experiments have shown that INCA1 also interacts with the testis protein RSB-66 and this interaction takes place in the cytoplasm. |
About INCA1 and Purified
| INCA1 | Enables cyclin binding activity; cyclin-dependent protein serine/threonine kinase inhibitor activity; and identical protein binding activity. Acts upstream of or within negative regulation of cyclin-dependent protein serine/threonine kinase activity. Located in cytoplasm and nuclear body. [provided by Alliance of Genome Resources, Apr 2022] |
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Citations
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