NR1H3 / DyLight 488 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB400-157G (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen NR1H3
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 488
Target Species Human, Mouse, Porcine, Primate
Applications WB
Description Rabbit LXR alpha/NR1H3 antibody [DyLight 488] detects Human, Mouse, Porcine, Primate
About NR1H3 and DyLight 488
NR1H3 The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra