EphB2 / Unconjugated /
EphB2 / Unconjugated /
Product Details
Supplier | Aviva Systems Biology | |
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Catalog #: | OAAF01517 (View supplier product page) | |
Size | 100 μg | |
Price | $289.00 | |
Antigen | EphB2 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Unconjugated | |
Target Species | Human, Mouse | |
Applications | WB, ELISA | |
Description | EPHB2 Antibody (OAAF01517) Unconjugated Rabbit Polyclonal Antibody, Reacts with Human, Mouse |
About EphB2 and Purified
EphB2 | This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015] |
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