POLG / Unconjugated /
POLG / Unconjugated /
Product Details
Supplier | Aviva Systems Biology | |
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Catalog #: | OAAJ11173 (View supplier product page) | |
Size | 100 μl | |
Price | $289.00 | |
Antigen | POLG | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Unconjugated | |
Target Species | Human, Mouse, Rat | |
Applications | WB, IHC | |
Description | POLG Antibody (OAAJ11173) Unconjugated Rabbit Polyclonal Antibody, Reacts with Human, Mouse, Rat |
About POLG and Purified
POLG | Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
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