Cdc25c / Unconjugated / 1F12
Cdc25c / Unconjugated / 1F12
Product Details
Supplier | Aviva Systems Biology | |
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Catalog #: | OALA03897 (View supplier product page) | |
Size | 50 μl | |
Price | $395.00 | |
Antigen | Cdc25c | |
Clone | 1F12 | |
Host | Mouse | |
Isotype | IgG1 | |
Conjugate | Unconjugated | |
Target Species | Human | |
Applications | IHC-P, WB, ELISA | |
Description | CDC25C, a CDC25 dual specificity protein phosphatase, has been shown to affect the regulation of cell cycle control, and specifically the G2/M progression, through interaction with cdc/cyclin kinases and proliferating cell nuclear antigen (PCNA). Unlike CDC25A and CDC25B, CDC25C does not seem to have oncogenic properties. CDC25C null mutant mice are viable, fertile, and do not display obvious abnomalities. |
About Cdc25c and Purified
Cdc25c | This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It also suppresses p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Dec 2015] |
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