NECAB3 / Unconjugated /
NECAB3 / Unconjugated /
Product Details
Supplier | Aviva Systems Biology | |
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Catalog #: | OAAJ04653 (View supplier product page) | |
Size | 100 μl | |
Price | $289.00 | |
Antigen | NECAB3 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Unconjugated | |
Target Species | Human, Mouse | |
Applications | WB, IF, ICC | |
Description | NECAB3 Antibody (OAAJ04653) Unconjugated Rabbit Polyclonal Antibody, Reacts with Human, Mouse |
About NECAB3 and Purified
NECAB3 | The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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