BEX3 / Unconjugated /
BEX3 / Unconjugated /
Product Details
| Supplier | Aviva Systems Biology | |
|---|---|---|
| Catalog #: | OALA04885 (View supplier product page) | |
| Size | 50 μg | |
| Price | $395.00 | |
| Antigen | BEX3 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Mouse | |
| Applications | IHC-P, WB | |
| Description | The p75 neurotrophin receptor (p75NTR) is a member of the tumor necrosis receptor superfamily and can mediate cell death and cell survival in response to nerve growth factor (NGF). The p75NTR-associated cell death executor (NADE) mediates apoptosis by interacting with the cell death domain of p75NTR following the binding of NGF by p75NTR. Recent studies have shown that NADE also interacts with second mitochondria-derived activator of caspase (Smac). |
About BEX3 and Purified
| BEX3 | Enables identical protein binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within extrinsic apoptotic signaling pathway via death domain receptors. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022] |
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Citations
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