YL1 / Unconjugated /
YL1 / Unconjugated /
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb127320-25ug (View supplier product page) | |
| Size | 25 μg | |
| Price | $119.00 | |
| Antigen | YL1 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Mouse | |
| Applications | ELISA, WB, IHC-P | |
| Description | Rabbit Polyclonal to VPS72. |
About YL1 and Purified
| YL1 | The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012] |
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Images
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Western blot analysis of extracts from RAW264.7 cells and NIH/3T3 cells using VPS72 antibody, Immunohistochemical analysis of formalin-fixed and paraffin-embedded human breast carcinoma tissue using VPS72 antibody |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$119.00
Supplier Page
Supplier Page
