CD268 / Biotin /

Product Details
Supplier Biorbyt
Catalog #: orb351388-100ug (View supplier product page)
Size 100 μg
Price $481.10
Antigen CD268
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Human
Applications ELISA
Description Rabbit polyclonal antibody against TNFRSF13C conjugated to Biotin
About CD268 and Biotin
CD268 B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008]
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Biotin Excitation and Emission Spectra