Sequestosome 1 / ATTO 633 /

Product Details
Supplier Biorbyt
Catalog #: orb384021-100ug (View supplier product page)
Size 100 μg
Price $577.00
Antigen Sequestosome 1
Clone
Host Rabbit
Isotype IgG
Conjugate ATTO 633
Target Species Human, Mouse
Applications WB
Description Rabbit polyclonal antibody against SQSTM1 conjugated to ATTO 633.
About Sequestosome 1 and ATTO 633
Sequestosome 1 This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009]
ATTO 633 ATTO 633 from ATTO-TEC has an excitation peak at 629 nm and an emission peak at 657 nm. ATTO 633 belongs to a new generation of fluorescent labels for the red spectral region. Characteristic features of the label are strong absorption, high fluorescence quantum yield, and high thermal and photo-stability. Thus ATTO 633 is highly suitable for single-molecule detection applications and high-resolution microscopy such as SIM, STED etc. Additionally the dye highly qualifies to be applied in flow cytometry (FACS), fluorescence in-situ hybridization (FISH) and many more. In common with most ATTO-labels, absorption and fluorescence are independent of pH, at least in the range of pH 2 to 11, used in typical applications. ATTO 633 is a cationic dye. After coupling to a substrate the label carries a net electrical charge of +1. The label is moderately hydrophilic.
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ATTO 633 Excitation and Emission Spectra