Perforin / Unconjugated /
Perforin / Unconjugated /
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb381984-50ul (View supplier product page) | |
| Size | 50 μl | |
| Price | $293.00 | |
| Antigen | Perforin | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Mouse | |
| Applications | WB, IF, ICC | |
| Description | Rabbit polyclonal antibody to PRF1. |
About Perforin and Purified
| Perforin | This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017] |
|---|
Images
|
Immunofluorescense analysis of K562 cells using PRF1 antibody, Western blot analysis of K562 (Lane1), mouse kidney (Lane2), mouse spleen (Lane3) whole cell lysates using PRF1 antibody |
Citations
| Additional Sources |
|
|---|
Reviews & Ratings
Purified Excitation and Emission Spectra
$293.00
Supplier Page
Supplier Page
