FluoroFinder

	Supplier	Biorbyt
	Catalog #:	orb304025-100ug (View supplier product page)
	Size	100 μg
	Price	$476.00
	Antigen	IL-18
	Clone	93-10C
	Host	Rat
	Isotype	IgG1
	Conjugate	Unconjugated
	Target Species	Mouse
	Applications	IP
	Description	Rat monoclonal antibody to IL18

	IL-18	The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020]