GPI / Unconjugated /

Product Details
Supplier Biorbyt
Catalog #: orb394231-20ul (View supplier product page)
Size 20 μl
Price $259.00
Antigen GPI
Clone
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Target Species Human
Applications ELISA, WB, IHC-P, IF, ICC
Description Mouse monoclonal antibody to Glucose-6-phosphate isomerase.
About GPI and Purified
GPI This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Purified Excitation and Emission Spectra