HAP1 / Biotin / 1B6

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB110-74569B (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen HAP1
Clone 1B6
Host Mouse
Isotype IgG1
Conjugate Biotin
Target Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC-P, IHC-Fr, IHC
Description This is specific for isoforms A and B.
About HAP1 and Biotin
HAP1 Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Biotin Excitation and Emission Spectra