Cathepsin L / Biotin /

Product Details
Supplier Biorbyt
Catalog #: orb350400-50ug (View supplier product page)
Size 50 μg
Price $343.40
Antigen Cathepsin L
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Primate
Applications ELISA
Description Rabbit polyclonal antibody against CTSL conjugated to Biotin
About Cathepsin L and Biotin
Cathepsin L The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Additionally, this protein cleaves the S1 subunit of the SARS-CoV-2 spike protein, which is necessary for entry of the virus into the cell. [provided by RefSeq, Aug 2020]
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Biotin Excitation and Emission Spectra