p190 / Unconjugated /
p190 / Unconjugated /
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb350373-20ug(TrialSize) (View supplier product page) | |
| Size | 20 μg | |
| Price | $85.00 | |
| Antigen | p190 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | ELISA | |
| Description | Rabbit polyclonal antibody to CNTNAP1 |
About p190 and Purified
| p190 | The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. [provided by RefSeq, Jan 2009] |
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Images
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Immunohistochemistry of paraffin-embedded human brain tissue using CNTNAP1 antibody , Immunohistochemistry of paraffin-embedded human testis tissue using CNTNAP1 antibody |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
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