Carbonic Anhydrase VIII / Unconjugated /
Carbonic Anhydrase VIII / Unconjugated /
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb235052-200ul (View supplier product page) | |
| Size | 200 μl | |
| Price | $404.60 | |
| Antigen | Carbonic Anhydrase VIII | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Monkey, Mouse | |
| Applications | WB, IHC-P | |
| Description | Rabbit polyclonal antibody to Carbonic Anhydrase 8 |
About Carbonic Anhydrase VIII and Purified
| Carbonic Anhydrase VIII | The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
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Images
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Western blot analysis of MCF7 (Lane 1), NS-1 (Lane 2) whole cell lysates using Carbonic Anhydrase 8 antibody, Immunohistochemical analysis of formalin-fixed and paraffin embedded human brain tissue using Carbonic Anhydrase 8 antibody |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$404.60
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