Bcl-6 / Unconjugated / SPM602

Product Details
Supplier Biorbyt
Catalog #: orb56175-20ug (View supplier product page)
Size 20 μg
Price $374.00
Antigen Bcl-6
Clone SPM602
Host Mouse
Isotype IgG1 κ
Conjugate Unconjugated
Target Species Human
Applications IHC-P, IF, ICC, FC
Description Mouse monoclonal antibody to Bcl6.
About Bcl-6 and Purified
Bcl-6 The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
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Purified Excitation and Emission Spectra