Bcl-10 / Unconjugated / 1185CT13.2.1.2
Bcl-10 / Unconjugated / 1185CT13.2.1.2
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb305763-400ul (View supplier product page) | |
| Size | 400 μl | |
| Price | $383.00 | |
| Antigen | Bcl-10 | |
| Clone | 1185CT13.2.1.2 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | ELISA, WB, IHC-P, FC | |
| Description | Mouse monoclonal antibody to BCL10 |
About Bcl-10 and Purified
| Bcl-10 | This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
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Images
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Flow cytometric analysis of Hela cells using BCL10 antibody (primary antibody dilution at: 1:25), Immunohistochemical staining of human kidney section tissue using BCL10 antibody (antibody dilution at 1:25), Immunohistochemical staining of paraffin embedded mouse kidney section tissue using BCL10 antibody (primary antibody dilution at: 1:25), Western blot analysis of Daudi cell lineusing BCL10 antibody (primary antibody dilution at: 1:2000) |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$383.00
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