ACK1 / Unconjugated /

Product Details
Supplier OriGene
Catalog #: AP17080PU-N (View supplier product page)
Size 400 μl
Price $330.00
Antigen ACK1
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications IHC, WB
Description Rabbit Polyclonal Anti-TNK2 Antibody
About ACK1 and Purified
ACK1 This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra