SUN2 / Unconjugated /

Product Details
Supplier OriGene
Catalog #: AP54462PU-N (View supplier product page)
Size 400 μl
Price $330.00
Antigen SUN2
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications WB
Description Rabbit Polyclonal Anti-SUN2 Antibody, Aff - Purified
About SUN2 and Purified
SUN2 SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]
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Purified Excitation and Emission Spectra