CD111 / Unconjugated / OTI6E11

Product Details
Supplier OriGene
Catalog #: TA503498 (View supplier product page)
Size 100 μl
Price $350.00
Antigen CD111
Clone OTI6E11
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Target Species Human
Applications WB, FC
Description PVRL1 mouse monoclonal antibody, clone OTI6E11 (formerly 6E11)
About CD111 and Purified
CD111 This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Purified Excitation and Emission Spectra