PSMC4 / Unconjugated /

Product Details
Supplier OriGene
Catalog #: TA345132 (View supplier product page)
Size 50 μg
Price $360.00
Antigen PSMC4
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Equine, Human, Mouse, Rabbit, Zebrafish
Applications WB
Description Rabbit Polyclonal Anti-PSMC4 Antibody - N-terminal region
About PSMC4 and Purified
PSMC4 The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
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Purified Excitation and Emission Spectra