PIK3C2A / Unconjugated / OTI2C10

Product Details
Supplier OriGene
Catalog #: CF801653 (View supplier product page)
Size 100 μg
Price $450.00
Antigen PIK3C2A
Clone OTI2C10
Host Mouse
Isotype IgG2a
Conjugate Unconjugated
Target Species Human
Applications WB, IHC
Description Carrier-free (BSA/glycerol-free) PIK3C2A mouse monoclonal antibody, clone OTI2C10 (formerly 2C10)
About PIK3C2A and Purified
PIK3C2A The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra