PSMB10 / Unconjugated /
PSMB10 / Unconjugated /
Product Details
Supplier | OriGene | |
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Catalog #: | TA305923 (View supplier product page) | |
Size | 100 μg | |
Price | $360.00 | |
Antigen | PSMB10 | |
Clone | ||
Host | Goat | |
Isotype | IgG | |
Conjugate | Unconjugated | |
Target Species | Human | |
Applications | WB, IHC | |
Description | Goat Anti-MECL1 Antibody |
About PSMB10 and Purified
PSMB10 | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq, Jul 2008] |
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Purified Excitation and Emission Spectra
$360.00
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