HLA-DOB / Unconjugated /

Product Details
Supplier OriGene
Catalog #: TA343166 (View supplier product page)
Size 50 μg
Price $360.00
Antigen HLA-DOB
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Bovine, Canine, Equine, Human, Porcine, Rabbit, Sheep
Applications WB
Description Rabbit Polyclonal Anti-HLA-DOB Antibody
About HLA-DOB and Purified
HLA-DOB HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra