Granulin / Unconjugated / OTI1F9

Product Details
Supplier OriGene
Catalog #: CF807352 (View supplier product page)
Size 100 μg
Price $450.00
Antigen Granulin
Clone OTI1F9
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Target Species Human
Applications WB, IHC
Description Carrier-free (BSA/glycerol-free) GRN mouse monoclonal antibody, clone OTI1F9 (formerly 1F9)
About Granulin and Purified
Granulin Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra