S100B / Biotin /

Product Details
Supplier Biorbyt
Catalog #: orb445923-100ug (View supplier product page)
Size 100 μg
Price $451.00
Antigen S100B
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Human, Mouse, Rat
Applications IHC-P, ELISA
Description Rabbit polyclonal antibody against S100B conjugated to Biotin
About S100B and Biotin
S100B The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]
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Biotin Excitation and Emission Spectra