FluoroFinder

	Supplier	Biorbyt
	Catalog #:	orb337932-50ul (View supplier product page)
	Size	50 μl
	Price	$357.00
	Antigen	RPL41
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human, Mouse, Rat
	Applications	WB
	Description	Rabbit polyclonal antibody to RPL41 also known as HG12, whose expression can be detected in the tongue but is highly expressive in the tonsils and amniotic fluid. It is found in the cytosolic large ribosomal subunit. This protein interacts with the beta subunit of protein kinase CK2 and stimulates phosphorylation of DNA topoisomerase II alpha by CK2. It also helps in the mRNA 3' 5'-UTR binding and nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.

	RPL41	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with the yeast ribosomal protein YL41, belongs to the L41E family of ribosomal proteins. It is located in the cytoplasm. The protein can interact with the beta subunit of protein kinase CKII and can stimulate the phosphorylation of DNA topoisomerase II-alpha by CKII. Two alternative splice variants have been identified, both encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]