RNF111 / Unconjugated /

Product Details
Supplier Biorbyt
Catalog #: orb500441-200ug (View supplier product page)
Size 200 μg
Price $610.30
Antigen RNF111
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications IHC-P, ELISA, ICC, IF
Description Rabbit polyclonal antibody to RNF111
About RNF111 and Purified
RNF111 The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]
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Purified Excitation and Emission Spectra