PTPN13 / Unconjugated /
PTPN13 / Unconjugated /
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb417067-100ug (View supplier product page) | |
| Size | 100 μg | |
| Price | $481.10 | |
| Antigen | PTPN13 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | ELISA, IHC-P, IF | |
| Description | Rabbit polyclonal antibody to PTPN13 |
About PTPN13 and Purified
| PTPN13 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Oct 2008] |
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Images
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Immunohistochemistry of paraffin-embedded human cervical cancer tissue using PTPN13 antibody , Immunofluorescence staining of A549 cells using PTPN13 antibody , Immunohistochemistry of paraffin-embedded human brain tissue using PTPN13 antibody |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$481.10
Supplier Page
Supplier Page
