ChT1 / PE / CT1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-28358 (View supplier product page)
Size 0.1 mg
Price $519.00
Antigen ChT1
Clone CT1
Host Mouse
Isotype IgG1 κ
Conjugate PE
Target Species Avian, Chicken
Applications FC, In Vitro, IP
Description ChT1 antigen (Mr 63/104 kDa) on chicken thymocytes
About ChT1 and PE
ChT1 This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Images
  ChT1 PE Novus Biologicals, a Bio-Techne brand antibody anti target:Avian, Chicken host:Mouse isotype:IgG1 κ clone:CT1 Flow Cytometry: ChT1 antigen Antibody (CT1) [PE] [NBP1-28358] - Chicken thymocytes were double st...

Flow Cytometry: ChT1 antigen Antibody (CT1) [PE] [NBP1-28358] - Chicken thymocytes were double stained with mouse anti-chicken CD3-PE and mouse antichicken ChT1-FITC. Analysis was performed on a Flow cytometer using a light scatter gate to identify small lymphocytes.

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PE Excitation and Emission Spectra