PRDM9 / Unconjugated /
PRDM9 / Unconjugated /
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb324624-100ul (View supplier product page) | |
| Size | 100 μl | |
| Price | $544.00 | |
| Antigen | PRDM9 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | WB, IHC-P | |
| Description | Rabbit polyclonal antibody to PRDM9 |
About PRDM9 and Purified
| PRDM9 | The protein encoded by this gene is a zinc finger protein with histone methyltransferase activity that catalyzes histone H3 lysine 4 trimethylation (H3K4me3) during meiotic prophase. This protein contains multiple domains, including a Kruppel-associated box (KRAB) domain, an SSX repression domain (SSXRD), a PRD1-BF1 and RIZ homologous region, a subclass of SET (PR/SET) domain, and a tandem array of C2H2 zinc fingers. The zinc finger array recognizes a short sequence motif, leading to local H3K4me3, and meiotic recombination hotspot activity. The observed allelic variation alters the DNA-binding sequence specificity of the protein, resulting in distinct meiotic recombination hotspots amongst individuals and populations. Multiple alternate alleles of this gene have been described. [provided by RefSeq, Jul 2015] |
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Images
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Western blot analysis of human HepG2 tissue using PRDM9 antibody, Western blot analysis of 293T cells lysate tissue using PRDM9 antibody, Immunohistochemical staining of human Testis tissue using PRDM9 antibody, Immunohistochemical staining of human Testis tissue using PRDM9 antibody, Immunohistochemical staining of human Placenta tissue using PRDM9 antibody, Western blot analysis of human 293T tissue using PRDM9 antibody, Western blot analysis of human MCF7 tissue using PRDM9 antibody |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
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