PLA2G4A / Unconjugated /
PLA2G4A / Unconjugated /
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb216174-200ul (View supplier product page) | |
| Size | 200 μl | |
| Price | $482.80 | |
| Antigen | PLA2G4A | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Monkey, Mouse | |
| Applications | WB, IHC-P, IF, ICC | |
| Description | Rabbit polyclonal antibody to PLA2G4A (pS505) |
About PLA2G4A and Purified
| PLA2G4A | This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] |
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Images
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Western blot analysis of HeLa lambda protein phosphatase-treated (Lane 1), NIH3T3 lambda protein phosphatase-treated (Lane 2) whole cell lysates using PLA2G4A antibody, Immunohistochemical analysis of formalin-fixed and paraffin-embedded human breast cancer tissue using PLA2G4A antibody (dilution at 1:200), Immunofluorescense analysis of HeLa cells lysates using PLA2G4A antibody |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$482.80
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