PIK3C2A / Unconjugated /

Product Details
Supplier Biorbyt
Catalog #: orb374187-50ul (View supplier product page)
Size 50 μl
Price $314.50
Antigen PIK3C2A
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications WB, IHC-P
Description Rabbit polyclonal antibody to PIK3C2A
About PIK3C2A and Purified
PIK3C2A The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008]
Images
  PIK3C2A Purified Biorbyt antibody anti target:Human, Mouse, Rat host:Rabbit isotype:IgG clone: Western blot analysis of extracts of various cells using PIK3C2A antibody, Immunohistochemical st...

Western blot analysis of extracts of various cells using PIK3C2A antibody, Immunohistochemical staining of mouse heart tissue using PIK3C2A antibody (dilution of 1:100), Immunohistochemical staining of rat heart tissue using PIK3C2A antibody (dilution of 1:100), Immunohistochemical staining of human liver injury tissue using PIK3C2A antibody (dilution of 1:100)

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Purified Excitation and Emission Spectra