Perforin / Unconjugated / dG9

Product Details
Supplier Biorbyt
Catalog #: orb222761-0.1mg (View supplier product page)
Size 100 μg
Price $395.00
Antigen Perforin
Clone dG9
Host Mouse
Isotype IgG2b
Conjugate Unconjugated
Target Species Human
Applications IHC-P, IHC-Fr, IF, ICC, IP, FC
Description Mouse monoclonal antibody to Perforin
About Perforin and Purified
Perforin This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
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Purified Excitation and Emission Spectra