p63 / Unconjugated /
p63 / Unconjugated /
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb214808-100ul (View supplier product page) | |
| Size | 100 μl | |
| Price | $258.40 | |
| Antigen | p63 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Canine, Human, Monkey, Mouse, Rat | |
| Applications | WB, IHC-P, IF, ICC | |
| Description | Rabbit polyclonal antibody to p63 |
About p63 and Purified
| p63 | This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. [provided by RefSeq, Aug 2016] |
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Images
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Western blot analysis of A549 (Lane 1), HCT116 (Lane 2), COLO205 (Lane 3), LOVO (Lane 4), HT29 (Lane 5) whole cell lysates using p63 antibody, Immunohistochemical analysis of formalin-fixed and paraffin-embedded human breast cancer tissue using p63 antibody (dilution at 1:200), Immunofluorescense analysis of A549 cells lysates using p63 antibody |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$258.40
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