p53 / Cy5 /

Product Details
Supplier Biorbyt
Catalog #: orb122836-100ug (View supplier product page)
Size 100 μg
Price $451.00
Antigen p53
Clone
Host Rabbit
Isotype IgG
Conjugate Cy5
Target Species Human, Mouse, Rat
Applications
Description Rabbit polyclonal antibody against p53 conjugated to Cy5.
About p53 and Cy5
p53 This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Cy5 Cy5 is an important historical fluorophore from GE Healthcare. It has an excitation peak at 649 nm and an emission peak at 667 nm. Spectrally its similar to Alexa Fluor™ 647.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Cy5 Excitation and Emission Spectra