EP300 / Unconjugated /

Product Details
Supplier OriGene
Catalog #: AP06548PU-N (View supplier product page)
Size 100 μg
Price $330.00
Antigen EP300
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications IHC, WB
Description Rabbit Polyclonal Anti-EP300 Antibody, Aff - Purified
About EP300 and Purified
EP300 This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra