CYP1A2 / Unconjugated / OTI1E12

Product Details
Supplier OriGene
Catalog #: CF501172 (View supplier product page)
Size 100 μg
Price $450.00
Antigen CYP1A2
Clone OTI1E12
Host Mouse
Isotype IgG2b
Conjugate Unconjugated
Target Species Human
Applications WB, IHC, IF, FC
Description Carrier-free (BSA/glycerol-free) CYP1A2 mouse monoclonal antibody, clone OTI1E12 (formerly 1E12)
About CYP1A2 and Purified
CYP1A2 This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra