COPS6 / Unconjugated / OTI4E7

Citations: (1)
Product Details
Supplier OriGene
Catalog #: TA505897 (View supplier product page)
Size 100 μl
Price $350.00
Antigen COPS6
Clone OTI4E7
Host Mouse
Isotype IgG2a
Conjugate Unconjugated
Target Species Human
Applications WB, IHC, IF
Description COPS6 mouse monoclonal antibody, clone OTI4E7 (formerly 4E7)
About COPS6 and Purified
COPS6 The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra