Bag3 / Unconjugated /

Citations: (1)
Product Details
Supplier OriGene
Catalog #: TA314928 (View supplier product page)
Size 100 μl
Price $335.00
Antigen Bag3
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications WB, IHC, ELISA
Description Rabbit polyclonal anti-BAG3 antibody
About Bag3 and Purified
Bag3 BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra