Alkaline Phosphatase / Unconjugated /

Product Details
Supplier OriGene
Catalog #: TA321138 (View supplier product page)
Size 100 μl
Price $335.00
Antigen Alkaline Phosphatase
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications ELISA, IHC
Description Anti-ALPL Rabbit Polyclonal Antibody
About Alkaline Phosphatase and Purified
Alkaline Phosphatase This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015]
Citations
Additional
Sources
Reviews & Ratings
Purified Excitation and Emission Spectra