MBD2 / Unconjugated /
MBD2 / Unconjugated /
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb330096-100ul (View supplier product page) | |
| Size | 100 μl | |
| Price | $451.00 | |
| Antigen | MBD2 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Canine, Equine, Guinea Pig, Human, Mouse, Rat, Zebrafish | |
| Applications | WB | |
| Description | Rabbit polyclonal antibody to MBD2 |
About MBD2 and Purified
| MBD2 | DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011] |
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Images
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Western blot analysis of mouse ES tissue using MBD2 antibody, Western blot analysis of HepG2 cell lysate tissue using MBD2 antibody |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$451.00
Supplier Page
Supplier Page
