FluoroFinder

	Supplier	Biorbyt
	Catalog #:	orb393100-30ul(Trialsize) (View supplier product page)
	Size	30 μl
	Price	$136.00
	Antigen	MAP3K8
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Bovine, Human, Monkey, Mouse, Rat
	Applications	WB, IHC-P, IF, ICC
	Description	Rabbit polyclonal antibody to MAP3K8.

	MAP3K8	This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]